Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50315426 ((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Competitive inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-alpha-methylglucoside uptake | Bioorg Med Chem 24: 1937-80 (2016) Article DOI: 10.1016/j.bmc.2016.03.004 BindingDB Entry DOI: 10.7270/Q22B90WR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20878 ((2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{2-[(4-methox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co Curated by ChEMBL | Assay Description Inhibition of human kidney SGLT2 assessed as renal glucose reabsorption | J Med Chem 52: 1785-94 (2009) Article DOI: 10.1021/jm8013019 BindingDB Entry DOI: 10.7270/Q2F47Q1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20878 ((2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{2-[(4-methox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co Curated by ChEMBL | Assay Description Inhibition of human kidney SGLT2 assessed as renal glucose reabsorption | J Med Chem 52: 1785-94 (2009) Article DOI: 10.1021/jm8013019 BindingDB Entry DOI: 10.7270/Q2F47Q1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20878 ((2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{2-[(4-methox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00867 BindingDB Entry DOI: 10.7270/Q2FB570W | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20877 (3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153302 (3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1-[2-hydroxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153312 (1-[2-Hydroxy-4-methyl-6-(3,4,5-trihydroxy-6-hydrox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153301 (3-(4-Ethoxy-phenyl)-1-[2-hydroxy-4-methyl-6-(3,4,5...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153305 (1-[4-Ethyl-2-hydroxy-6-(3,4,5-trihydroxy-6-hydroxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153298 (3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1-[4-ethyl-2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50559516 (GSK-189075 | GSK-189075A | GSK189075A | Remogliflo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Antagonist potency against adenosine A2B receptor of guinea pig thoracic aortic smooth muscle | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50257747 (CHEMBL494322 | remogliflozin) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co Curated by ChEMBL | Assay Description Inhibition of human kidney SGLT2 assessed as renal glucose reabsorption | J Med Chem 52: 1785-94 (2009) Article DOI: 10.1021/jm8013019 BindingDB Entry DOI: 10.7270/Q2F47Q1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50257747 (CHEMBL494322 | remogliflozin) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co Curated by ChEMBL | Assay Description Inhibition of human kidney SGLT2 assessed as renal glucose reabsorption | J Med Chem 52: 1785-94 (2009) Article DOI: 10.1021/jm8013019 BindingDB Entry DOI: 10.7270/Q2F47Q1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co Curated by ChEMBL | Assay Description Inhibition of human kidney SGLT2 assessed as renal glucose reabsorption | J Med Chem 52: 1785-94 (2009) Article DOI: 10.1021/jm8013019 BindingDB Entry DOI: 10.7270/Q2F47Q1T | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153293 (1-[4-Chloro-2-hydroxy-6-(3,4,5-trihydroxy-6-hydrox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153309 (3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1-[2-hydroxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153294 (3-(4-Ethoxy-phenyl)-1-[4-ethyl-2-hydroxy-6-(3,4,5-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153296 (1-[4-Chloro-2-hydroxy-6-(3,4,5-trihydroxy-6-hydrox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153313 (3-Cyclohexyl-1-[2-hydroxy-4-methyl-6-(3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM20877 (3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153292 (1-[4-Fluoro-2-hydroxy-6-(3,4,5-trihydroxy-6-hydrox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153306 (1-[2-Hydroxy-4-methyl-6-(3,4,5-trihydroxy-6-hydrox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153299 (1-[4-Chloro-2-hydroxy-6-(3,4,5-trihydroxy-6-hydrox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM50595439 (CHEMBL5178665) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 97 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00867 BindingDB Entry DOI: 10.7270/Q2FB570W | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153304 (3-(4-Ethoxy-phenyl)-1-[2-hydroxy-4-isopropyl-6-(3,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153307 (1-[2-Hydroxy-4-isopropyl-6-(3,4,5-trihydroxy-6-hyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50351429 (CHEMBL450044) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 151 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00867 BindingDB Entry DOI: 10.7270/Q2FB570W | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Max-Planck-Institut f£r molekulare Physiologie Curated by ChEMBL | Assay Description Binding affinity against Sodium/glucose co-transporter of isolated renal brush border membranes. | J Med Chem 43: 1692-8 (2000) BindingDB Entry DOI: 10.7270/Q261112H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153303 (3-Furan-3-yl-1-[2-hydroxy-4-methyl-6-(3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153311 (1-[2-Amino-4-methyl-6-(3,4,5-trihydroxy-6-hydroxym...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153308 (1-[2-Amino-4-methyl-6-(3,4,5-trihydroxy-6-hydroxym...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 520 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM50422357 (CHEMBL2303984) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Max-Planck-Institut f£r molekulare Physiologie Curated by ChEMBL | Assay Description Binding affinity against Sodium/glucose co-transporter of isolated renal brush border membranes. | J Med Chem 43: 1692-8 (2000) BindingDB Entry DOI: 10.7270/Q261112H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM20878 ((2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{2-[(4-methox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 708 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00867 BindingDB Entry DOI: 10.7270/Q2FB570W | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM50153313 (3-Cyclohexyl-1-[2-hydroxy-4-methyl-6-(3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153297 (1-[2-Amino-4-methyl-6-(3,4,5-trihydroxy-6-hydroxym...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM50153312 (1-[2-Hydroxy-4-methyl-6-(3,4,5-trihydroxy-6-hydrox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM50153306 (1-[2-Hydroxy-4-methyl-6-(3,4,5-trihydroxy-6-hydrox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM50153302 (3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1-[2-hydroxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM50153301 (3-(4-Ethoxy-phenyl)-1-[2-hydroxy-4-methyl-6-(3,4,5...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153300 (1-[2-Chloro-6-(3,4,5-trihydroxy-6-hydroxymethyl-te...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | >1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153295 (1-[2-Chloro-6-(3,4,5-trihydroxy-6-hydroxymethyl-te...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | >1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153310 (1-[2-Chloro-6-(3,4,5-trihydroxy-6-hydroxymethyl-te...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | >1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM50087823 (1-[2-(4,5-Dihydroxy-6-hydroxymethyl-tetrahydro-pyr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Max-Planck-Institut f£r molekulare Physiologie Curated by ChEMBL | Assay Description Binding affinity against Sodium/glucose co-transporter of isolated renal brush border membranes. | J Med Chem 43: 1692-8 (2000) BindingDB Entry DOI: 10.7270/Q261112H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM50422353 (CHEMBL2303988) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Max-Planck-Institut f£r molekulare Physiologie Curated by ChEMBL | Assay Description Binding affinity against Sodium/glucose co-transporter of isolated renal brush border membranes. | J Med Chem 43: 1692-8 (2000) BindingDB Entry DOI: 10.7270/Q261112H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM50153292 (1-[4-Fluoro-2-hydroxy-6-(3,4,5-trihydroxy-6-hydrox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM50153293 (1-[4-Chloro-2-hydroxy-6-(3,4,5-trihydroxy-6-hydrox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM50422355 (CHEMBL2303989) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Max-Planck-Institut f£r molekulare Physiologie Curated by ChEMBL | Assay Description Binding affinity against Sodium/glucose co-transporter of isolated renal brush border membranes. | J Med Chem 43: 1692-8 (2000) BindingDB Entry DOI: 10.7270/Q261112H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM50153303 (3-Furan-3-yl-1-[2-hydroxy-4-methyl-6-(3,4,5-trihyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 4.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM50559516 (GSK-189075 | GSK-189075A | GSK189075A | Remogliflo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | 4.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Antagonist potency at cloned recombinant human adenosine A2B receptor transfected in CHO cells by cAMP assay | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (Homo sapiens (Human)) | BDBM50153299 (1-[4-Chloro-2-hydroxy-6-(3,4,5-trihydroxy-6-hydrox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 4.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair |
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